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Related Experiment Video

Updated: Sep 29, 2025

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

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Acute-Phase Stroke Outcome and Lipids.

Osman Serhat Tokgoz¹, Figen Guney¹, Ahmet Kaya²

¹Department of Neurology, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey.

Sisli Etfal Hastanesi Tip Bulteni

|March 23, 2022

Summary

This summary is machine-generated.

Lower triglyceride and triglyceride/HDL-C levels in acute stroke patients may predict short-term mortality. This finding differs from long-term stroke risk factors, highlighting TG as a potential mortality indicator in acute conditions.

Keywords:

Malnutrition mortality stroke triglyceride

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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

Neurology
Cardiology
Biochemistry

Background:

Dyslipidemia is a recognized risk factor for stroke.
Understanding acute stroke patient outcomes is crucial for timely intervention.

Purpose of the Study:

To investigate the association between lipid subgroups and short-term mortality in acute stroke (AS) patients.
To identify lipid parameters that may predict mortality within 30 days of stroke onset.

Main Methods:

Retrospective analysis of 698 acute stroke patients admitted within 24 hours of symptom onset.
Recorded lipid profiles including Total Cholesterol (TC), Triglyceride (TG), HDL-C, LDL-C, TC/HDL-C, and TG/HDL-C.
Follow-up period of 30 days to assess mortality.

Main Results:

Sixty-four out of 698 patients died within the 30-day follow-up.
Lower mean levels of TG, TG/HDL-C, and TC/HDL-C were observed in the non-survivor group.
Receiver Operating Characteristic (ROC) analysis identified TG and TG/HDL-C as significant predictors of short-term mortality.

Conclusions:

Lower triglyceride and triglyceride/HDL-C levels at hospital admission may predict short-term mortality in acute stroke patients.
This contrasts with established long-term stroke risk factors, suggesting TG's utility in hypercatabolic states like stroke.
Serum triglyceride levels may serve as a valuable indicator for mortality in acute stroke.