Related Experiment Video
Updated: Sep 29, 2025

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
[True posterior infarction diagnosis. Report of three cases]
Fernando Pineda1, Bruno Dighero2, Jorge Meruane2
1Cardiología y Hemodinamia, Clínica las Condes, Santiago, Chile.
Insights
ST-elevation myocardial infarction (STEMI) requires prompt reperfusion. True Posterior Infarction (TPI) diagnosis is challenging using standard EKGs, necessitating posterior leads or mirror imaging for accurate identification and timely treatment.
Area of Science:
- Cardiology
- Electrocardiography
- Emergency Medicine
Background:
- ST-segment elevation myocardial infarction (STEMI) demands rapid reperfusion.
- Accurate electrocardiogram (EKG) interpretation is critical for timely therapeutic decisions in acute coronary syndromes.
Observation:
- Three cases of True Posterior Infarction (TPI) presented diagnostic challenges.
- The standard 12-lead EKG was insufficient for diagnosing these TPI cases.
Findings:
- Posterior leads on an EKG can aid in diagnosing TPI.
- Observing inverted leads V1-V3 on a standard EKG may suggest posterior infarction.
Implications:
- Early identification of TPI is crucial for initiating appropriate reperfusion therapy.
- Integrating posterior leads or mirror imaging into routine EKG interpretation can improve TPI diagnosis.
- Enhanced EKG diagnostic strategies can improve outcomes for patients with posterior myocardial infarction.
Abstract:
Acute Coronary Syndrome with ST segment elevation requires rapid reperfusion, which is why the timely identification of these conditions, based on the patient's symptoms and the correct interpretation of the EKG, is essential for therapeutic decisions. We report three patients with True Posterior Infarction and their difficult EKG diagnosis. The classic 12-lead EKG method is often not capable of supporting the diagnosis, so we recommend the use of posterior leads and mirror images observing inverted V1-V2-V3 leads on the classic EKG.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Acute Coronary Syndrome I: Introduction

