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Related Concept Videos

IR Frequency Region: Fingerprint Region01:03

IR Frequency Region: Fingerprint Region

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IR spectra are divided into two main regions: the diagnostic region and the fingerprint region. The diagnostic region of the spectrum lies above 1500 cm−1. The absorptions resulting from single-bond vibrations of the N–H, C–H, and O–H stretch at higher wavenumbers and appear on the left side of the spectrum. The stretching absorptions of the C≡C and C≡N occur between 2100–2300 cm−1. In contrast, those arising from stretching absorptions of the...
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Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
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3D MR fingerprinting using Seiffert spirals.

Cory R Wyatt1,2, Alexander R Guimaraes1,2

  • 1Department of Diagnostic Radiology, Oregon Health & Sciences University, Portland, Oregon, USA.

Magnetic Resonance in Medicine
|March 24, 2022
PubMed
Summary
This summary is machine-generated.

Seiffert spirals enhance 3D MR fingerprinting (MRF) for faster, high-resolution T1 and T2 mapping. This novel approach reduces artifacts, improving quantification and scan times for advanced MRI applications.

Keywords:
MR fingerprintingbrainrelaxometry

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Area of Science:

  • Magnetic Resonance Imaging
  • Quantitative MRI
  • Biomedical Engineering

Background:

  • 3D MR fingerprinting (MRF) enables rapid acquisition of T1 and T2 relaxation maps.
  • Traditional MRF sequences may not fully sample 3D k-space efficiently per TR.
  • Seiffert spirals offer an efficient method for 3D k-space traversal.

Purpose of the Study:

  • To develop and evaluate a 3D MRF sequence utilizing Seiffert spirals for T1 and T2 mapping.
  • To compare the performance of Seiffert spiral MRF against conventional 2D spiral MRF sequences.

Main Methods:

  • A 3D MRF sequence with 8 rotated Seiffert spirals and flip angle modulation was designed.
  • The Seiffert spiral sequence was compared to a 2D spiral MRF sequence with tiny golden angle acquisition.
  • Evaluation involved simulations, phantom studies, and in vivo imaging.

Main Results:

  • The Seiffert spiral MRF sequence performed comparably to or better than the 2D spiral MRF sequence.
  • High intraclass correlation coefficients (>0.9) were observed between conventional and MRF sequences in phantoms.
  • In vivo imaging demonstrated reduced aliasing artifacts with the Seiffert trajectory.

Conclusions:

  • Seiffert spirals integrated into MRF acquire high-resolution T1 and T2 maps in under 2.5 minutes.
  • Even sampling of 3D k-space using Seiffert trajectories improves quantification and reduces scan times.
  • This technique holds promise for accelerated quantitative MRI.