Comparison Study of the Two Biometers Based on Swept-Source Optical Coherence Tomography Technology.

Area of Science:

• Ophthalmology
• Medical Devices
• Optical Coherence Tomography

Background:

• Accurate biometry is crucial for successful intraocular lens (IOL) power calculation in cataract surgery.
• Swept-source optical coherence tomography (SS-OCT) biometers are widely used for ophthalmic measurements.

Purpose of the Study:

• To compare key biometric parameters measured by two different SS-OCT biometers: ANTERION (biometer A) and IOLMaster 700 (biometer B).
• To assess potential differences in intraocular lens (IOL) power calculations derived from these two devices.

Main Methods:

• A prospective observational comparative case series study involving 179 eyes undergoing cataract surgery.
• Measurements included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), keratometry (Kf, Ks, Km), astigmatism, white-to-white (WTW) distance, and IOL power.
• Paired t-tests and McNemar tests were used for statistical comparison.

Main Results:

• No significant difference was found in axial length (AL) or astigmatism magnitude between the two biometers.
• Significant differences were observed in CCT, ACD, LT, keratometry (Kf, Ks, Km), WTW distance, astigmatism axis, and IOL power.
• Approximately 65.4% of eyes showed a ≥0.5-D difference in IOL power between devices.

Conclusions:

• The ANTERION and IOLMaster 700 SS-OCT biometers exhibit significant measurement differences for most ocular parameters, excluding AL.
• These discrepancies, particularly in IOL power, may impact refractive outcomes following cataract surgery and warrant careful consideration.