Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hemodialysis II: Procedure and Complications

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

Hemodialysis I: Introduction

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...

Dialysis

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...

Ion Exchange

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...

Hemodialysis III: Nursing Management

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Covalent Immobilization of Crown Ether on Cellulose Acetate Membranes for Enhanced Heavy Metal Ion Retention.

Polymers·2026

Same author

Cellulose Acetate/Hydroxyapatite-Dexamethasone Loaded Membranes for the Prevention of Implant-Associated Acute Inflammation.

Polymers·2026

Same author

Crown Ether-Functionalized Polyethersulfone Membranes with Potential Applications in Hemodialysis.

Polymers·2025

Same author

Improved Biomineralization Using Cellulose Acetate/Magnetic Nanoparticles Composite Membranes.

Polymers·2025

Same author

Robust CA-GO-TiO<sub>2</sub>/PTFE Photocatalytic Membranes for the Degradation of the Azithromycin Formulation from Wastewaters.

Polymers·2024

Same author

Biocompatible Composite Filaments Printable by Fused Deposition Modelling Technique: Selection of Tuning Parameters by Influence of Biogenic Hydroxyapatite and Graphene Nanoplatelets Ratios.

Biomimetics (Basel, Switzerland)·2024

Search research articles

Related Experiment Video

Updated: Sep 29, 2025

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility.

Elena Ruxandra Radu^1,2, Stefan Ioan Voicu^1,2

¹Advanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.

|March 26, 2022

Summary

This review explores functionalizing polysulfone membranes to improve hemocompatibility and efficiency in hemodialysis, enhancing patient outcomes and reducing bodily impact.

Keywords:

composite membranes covalent functionalization hemodialysis polysulfone

More Related Videos

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits

Published on: August 20, 2014

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Published on: March 5, 2020

Related Experiment Videos

Last Updated: Sep 29, 2025

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits

Published on: August 20, 2014

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Published on: March 5, 2020

Area of Science:

Materials Science
Biomedical Engineering
Chemical Engineering

Background:

Membrane technology is crucial for desalination and hemodialysis.
Hemodialysis significantly improves life expectancy for chronic kidney dysfunction patients.
Ensuring hemocompatibility of membranes is a major challenge in hemodialysis.

Purpose of the Study:

To review the latest research on functionalizing polysulfone membranes.
To enhance hemocompatibility and separation efficiency of hemodialysis membranes.
To minimize the impact of hemodialysis on the patient's body.

Main Methods:

Focuses on functionalization strategies for polysulfone membranes.
Reviews advancements in material science for membrane preparation.
Analyzes methods to improve blood-membrane interactions.

Main Results:

Functionalization increases hemocompatibility of polysulfone membranes.
Improved separation efficiency is achieved through advanced membrane design.
Reduced negative impacts on blood during hemodialysis are reported.

Conclusions:

Functionalized polysulfone membranes offer improved hemodialysis performance.
Continued research in membrane functionalization is vital for patient care.
Optimizing membrane properties balances efficiency with hemocompatibility.