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Subacute neurological sequelae in mild COVID-19 outpatients
Aslihan Taskiran-Sag1, Erdal Eroğlu1, Şule Canlar2
1Clinic of Neurology, TOBB ETU Medical Faculty Hospital, Ankara, Turkey.
Tuberkuloz Ve Toraks
|April 1, 2022
Summary
Neurological symptoms like headache and cognitive dysfunction are common in mild COVID-19 survivors. These long COVID neurological sequelae can emerge even without acute symptoms.
Area of Science:
- Neurology
- Infectious Diseases
- Public Health
Background:
- Neurological manifestations of COVID-19 are not fully understood.
- Mild COVID-19 cases can lead to persistent neurological issues.
- Subacute neurological sequelae require further investigation.
Purpose of the Study:
- To define subacute neurological sequelae in patients with mild COVID-19.
- To identify common neurological complaints post-mild COVID-19 infection.
- To explore the relationship between acute and subacute neurological symptoms.
Main Methods:
- Enrolled non-hospitalized mild COVID-19 patients with neurological complaints.
- Conducted detailed history, neurological examination, and blood tests.
- Utilized descriptive statistics, Chi-square, and Student's t-test.
Main Results:
- Headache and cognitive dysfunction were the most frequent subacute complaints (42% each).
- Sleep disturbance (36%), prolonged anosmia (30%), and fatigue (22%) were also common.
- Subacute symptoms occurred in a young cohort (mean age 36.9), with no clear link to inflammatory markers or acute pulmonary involvement.
Conclusions:
- Mild COVID-19 can result in significant subacute neurological sequelae, notably headache and cognitive dysfunction.
- These neurological issues affect a relatively young population.
- Further research is needed to understand the long-term impact and mechanisms of these sequelae.
