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A NEW METHOD FOR ESTIMATING INCREASE IN RADIATION DOSE ASSOCIATED WITH IODINATED CONTRAST USE
Qiang Wang1, Qiang Fu1, Cong Pang2
1Department of Occupational Disease Prevention, Changzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Radiation Protection Dosimetry
|April 3, 2022
Summary
Iodinated contrast media (ICM) significantly increase radiation dose in computed tomography (CT) scans. This study developed and validated models linking CT numbers to organ dose increases from ICM.
Area of Science:
- Medical Physics
- Radiology
- Radiation Dosimetry
Background:
- Iodinated contrast media (ICM) are widely used in computed tomography (CT) for enhanced imaging.
- The impact of ICM on radiation dose, particularly organ dose, requires precise quantification.
- Existing methods for dose estimation may not fully account for the attenuation properties of ICM.
Purpose of the Study:
- To investigate and quantify the impact of iodinated contrast medium (ICM) on radiation dose in CT scans.
- To establish and validate linear models correlating CT numbers with absorbed radiation dose in the presence of ICM.
- To determine the extent of organ dose increase due to ICM administration in CT examinations.
Main Methods:
- A phantom study was conducted using thermoluminescence dosemeters (TLDs) and semi-conductor X-ray dosemeters for calibration.
- Electron density phantoms with varying concentrations of iodinated blood were scanned at different tube voltages.
- Linear models were developed by plotting CT numbers against absorbed doses, and subsequently validated using data from 49 patient scans.
Main Results:
- A strong linear correlation was observed between CT numbers and absorbed doses across different X-ray energies.
- Increased blood iodine concentration directly correlated with higher CT numbers and increased absorbed radiation dose.
- Significant average organ dose increases were reported: thyroid (31.8%), cardiac muscle (37.1%), cardiac chamber (77.7%), breast (7.1%), liver (26.1%), spleen (39.8%), renal cortex (96.3%), and medulla nephrica (82.4%).
Conclusions:
- Iodinated contrast media administration in enhanced CT scans leads to a notable increase in organ radiation doses.
- The developed linear models, based on CT numbers, provide a reliable method for estimating organ dose increases caused by ICM.
- These validated models can aid in optimizing CT protocols and managing radiation exposure in contrast-enhanced imaging.
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