Related Experiment Video
Updated: Sep 28, 2025
13:24
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
11.9K
Think Globally, Act Locally: Globalizing Precision Oncology
Justin T Moyers1, Vivek Subbiah2,3,4
1Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, Orange, California.
Cancer Discovery
|April 4, 2022
Summary
Globalizing precision oncology is crucial for future cancer care. The K-MASTER study offers a model for East Asian infrastructure, demonstrating precision oncology's worldwide potential.
Area of Science:
- Oncology
- Genomics
- Healthcare Infrastructure
Background:
- Precision oncology aims to tailor treatments to individual patients based on genetic profiles.
- Globalizing precision oncology requires robust infrastructure and collaborative frameworks.
- The K-MASTER study addresses these needs in the East Asian context.
Discussion:
- The K-MASTER study presents a practical framework for implementing precision oncology infrastructure.
- This framework highlights the importance of regional collaboration and data sharing.
- Adapting the precision oncology approach to diverse healthcare systems is essential.
Key Insights:
- The K-MASTER study provides a blueprint for building precision oncology capabilities in East Asia.
- Successful globalization of precision oncology necessitates a "think globally, act locally" strategy.
- Infrastructure development is a critical enabler for equitable access to precision cancer care.
Outlook:
- Expanding precision oncology globally requires addressing disparities in healthcare access and resources.
- Future efforts should focus on creating sustainable models for precision oncology implementation worldwide.
- International cooperation will accelerate the adoption of personalized cancer treatments.
Related Concept Videos
02:50Combination Therapies and Personalized Medicine
5.1K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.1K
02:56Treatment Resistant Cancers
3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K