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Related Concept Videos

Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

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Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
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Updated: Sep 27, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Offering an Off-Label Therapeutic Algorithm for Lichen Planus.

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    |April 7, 2022
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    Summary
    This summary is machine-generated.

    Lichen planus (LP) is a chronic inflammatory skin condition characterized by itchy, polygonal bumps and lesions on the skin and mucous membranes. This poorly understood dermatosis requires further research for effective management.

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    Area of Science:

    • Dermatology
    • Immunology
    • Inflammatory Diseases

    Background:

    • Lichen planus (LP) is a chronic inflammatory dermatosis with incompletely understood characteristics.
    • LP presents with distinctive clinical features, including pruritic papules and plaques, often with characteristic scaling and mucosal erosions.

    Purpose of the Study:

    • To elucidate the poorly characterized nature of lichen planus.
    • To detail the clinical presentation and diagnostic features of lichen planus.

    Main Methods:

    • Clinical observation and documentation of characteristic lesions.
    • Histopathological examination of affected tissues (not explicitly stated but implied for dermatosis characterization).

    Main Results:

    • Lichen planus is defined by violaceous to brown/black polygonal, pruritic papules and plaques.
    • Lesions frequently exhibit a lacy scale and reticular white erosions, particularly on mucosal surfaces.

    Conclusions:

    • Lichen planus is a distinct chronic inflammatory dermatosis.
    • Accurate characterization of LP's clinical manifestations is crucial for diagnosis and management.