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Atrial Failure: What Do We Know About It?
Sidhi Laksono Purwowiyoto1, Budhi Setianto, Steven Philip Surya
11. Siloam Diagram Heart Hospital, Cinere, Depok, Indonesia. 2. Faculty of Medicine, Universitas Muhammadiyah Prof. DR. Hamka, Tangerang, Indonesia. sidhilaksono@uhamka.ac.id.
Acta Medica Indonesiana
|April 10, 2022
Summary
Heart failure can occur without left ventricle dysfunction, challenging traditional views. Left atrial dysfunction is increasingly recognized as a significant, independent contributor to heart failure development.
Area of Science:
- Cardiology
- Pathophysiology
Background:
- Heart failure is typically associated with left ventricular dysfunction.
- Emerging evidence suggests heart failure can manifest without preceding left ventricular dysfunction.
Purpose of the Study:
- To review the complex role of left atrial dysfunction in heart failure.
- To elucidate the etiology, pathomechanism, and clinical presentation of atrial failure.
Main Methods:
- Literature review of current clinical studies and accepted paradigms.
- Analysis of the independent contribution of left atrial function to global heart failure.
Main Results:
- Left atrial dysfunction can precede and occur independently of left ventricular dysfunction.
- Atrial failure, similar to left ventricular failure, can lead to global heart failure.
Conclusions:
- Left atrial dysfunction represents a critical, often overlooked, factor in heart failure.
- Further research is needed to fully understand the mechanisms and clinical implications of atrial failure.
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