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Updated: Sep 27, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Atrial Failure: What Do We Know About It?
Sidhi Laksono Purwowiyoto1, Budhi Setianto, Steven Philip Surya
11. Siloam Diagram Heart Hospital, Cinere, Depok, Indonesia. 2. Faculty of Medicine, Universitas Muhammadiyah Prof. DR. Hamka, Tangerang, Indonesia. sidhilaksono@uhamka.ac.id.
Insights
Heart failure can occur without left ventricle dysfunction, challenging traditional views. Left atrial dysfunction is increasingly recognized as a significant, independent contributor to heart failure development.
Area of Science:
- Cardiology
- Pathophysiology
Background:
- Heart failure is typically associated with left ventricular dysfunction.
- Emerging evidence suggests heart failure can manifest without preceding left ventricular dysfunction.
Purpose of the Study:
- To review the complex role of left atrial dysfunction in heart failure.
- To elucidate the etiology, pathomechanism, and clinical presentation of atrial failure.
Main Methods:
- Literature review of current clinical studies and accepted paradigms.
- Analysis of the independent contribution of left atrial function to global heart failure.
Main Results:
- Left atrial dysfunction can precede and occur independently of left ventricular dysfunction.
- Atrial failure, similar to left ventricular failure, can lead to global heart failure.
Conclusions:
- Left atrial dysfunction represents a critical, often overlooked, factor in heart failure.
- Further research is needed to fully understand the mechanisms and clinical implications of atrial failure.
Abstract:
Heart failure is the end of all pathological conditions in the heart. Most accepted paradigms in heart failure are always preceded by left ventricle disfunction. Currently, there are several clinical studies that show that heart failure may occur without prior left ventricular dysfunction. Left atrial dysfunction may play a more important role in heart failure than previously expected. Failure of the left atrium can exist independently of left ventricle dysfunction and mitral valve abnormalities. Atrial failure, just like left ventricular failure, can lead to global heart failure. Etiology, pathomechanism and clinical symptoms of atrial failure are complex and not well understood. This review will explain atrial failure.
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