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Updated: Sep 27, 2025
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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
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Doses, fractionations, constraints for stereotactic radiotherapy.
Simona Borghesi1, Cynthia Aristei2, Francesco Marampon3
1Radiation Oncology Unit of Arezzo-Valdarno, Azienda USL Toscana Sud Est, Italy.
Summary
This study guides stereotactic radiotherapy (SRT) dose selection based on lesion characteristics and organs at risk. It details dose prescriptions, delivery, and planning parameters for optimal treatment coverage and safety.
Area of Science:
- Radiation Oncology
- Medical Physics
Background:
- Stereotactic radiotherapy (SRT) requires precise dose and fractionation selection.
- Lesion characteristics, organs at risk (OARs), and biological effective dose are critical factors.
Purpose of the Study:
- To provide guidance on selecting appropriate stereotactic radiotherapy dose and fractionation schemes.
- To detail dose prescription, delivery, and planning parameters for optimal treatment outcomes.
Main Methods:
- Review of International Commission on Radiation Units and Measurements (ICRU) Report No. 91 for SRT.
- Analysis of dose ranges for single-dose (15-34 Gy) and fractionated SRT (30-75 Gy).
- Inclusion of OAR dose constraints, treatment planning system characteristics, and irradiation geometry.
Main Results:
- Established dose ranges for single and fractionated SRT.
- Defined optimal coverage as the best planning target volume coverage achievable.
- Provided recommendations for calculation algorithms, beam energy, and multileaf collimator leaf size.
Conclusions:
- The paper offers a comprehensive framework for SRT dose and fractionation selection.
- Adherence to recommended parameters ensures optimal target coverage and OAR safety.
- ICRU Report No. 91 serves as a key reference for SRT treatment planning.
