Cholesterol Granuloma: An Underrecognized Cause of Benign Lung Granuloma

A cholesterol granuloma is a benign lesion that can occur in various organs, mimicking other pathologies. We present the case of a 35-year-old man presenting with asymptomatic lung and pleural lesions which were suspected to be pulmonary tuberculosis but found to be cholesterol granuloma on biopsy. Cholesterol granulomas are a rare mimic of common lung pathology and should be considered in the differential diagnosis if the initial investigations are not informative.

Pulmonary cholesterol granuloma is a benign lesion that radiologically mimics many sinister pathologies.The pathogenesis of pulmonary cholesterol granuloma remains obscure and extensive work-up is usually needed to rule out malignancy and infectious aetiology.