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NIR-I-Responsive Single-Band Upconversion Emission through Energy Migration in Core-Shell-Shell Nanostructures.

Mingye Ding1, Songsong Cui1, Liang Fang2

  • 1Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Science, Nanjing Forestry University, Nanjing, 210037, China.

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Summary
This summary is machine-generated.

We developed novel upconversion nanoparticles (UCNPs) for enhanced bioimaging. These UCNPs efficiently emit red light in the near-infrared biowindow, overcoming traditional limitations.

Keywords:
Back EnergytransferBiophotonicsCore@Shell@ShellEnergy MigrationUpconversion

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Engineering

Background:

  • Upconversion nanoparticles (UCNPs) are crucial for bioimaging due to their ability to convert near-infrared (NIR) light to visible light.
  • Tuning UCNPs emission to the first infrared biowindow (NIR-I) is essential for deep tissue penetration and reduced autofluorescence.
  • Existing UCNPs often suffer from low efficiency and undesired emission colors, limiting their bioapplication potential.

Purpose of the Study:

  • To develop a new strategy for tuning UCNP excitation and emission into the NIR-I region (650-900 nm).
  • To achieve high NIR-I-to-NIR-I upconversion efficiency.
  • To eliminate back energy transfer (BET) and undesired green emission for enhanced red upconversion.

Main Methods:

  • Designed a core-shell-shell nanoarchitecture incorporating Nd3+, Er3+, Yb3+, and Mn2+ ions.
  • Engineered specific energy migration pathways within the UCNP structure.
  • Utilized 808 nm NIR-I laser excitation to induce upconversion.

Main Results:

  • Achieved efficient single-band red upconversion emission.
  • Successfully tuned both excitation and emission peaks into the NIR-I biowindow.
  • Completely eliminated BET-induced photon quenching and green emission.

Conclusions:

  • The novel UCNP strategy effectively blocks BET and promotes red emission.
  • This advancement provides high-efficiency NIR-I to red upconversion for bioimaging.
  • The findings offer fundamental insights into lanthanide interactions and UCNP development for bioapplications.