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Managing Apoptosis in Lung Diseases using Nano-assisted Drug Delivery System.
Monu K Shukla1, Amit Dubey2,3, Sadanand Pandey4
1Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan-173229, Himachal Pradesh, India.
Current Pharmaceutical Design
|April 15, 2022
Summary
Nanotechnology offers improved lung cancer treatment by enhancing drug delivery and reducing side effects. Advanced nanocarriers enable personalized therapies, targeting tumor resistance and improving patient outcomes.
Area of Science:
- Oncology
- Nanotechnology
- Drug Delivery
Background:
- Lung cancer treatment efficacy is limited by factors like poor drug delivery, tumor resistance, and individual patient profiles.
- Conventional therapies often face challenges in achieving targeted delivery and overcoming biological barriers within the lungs.
Approach:
- This review critically examines nano-enabled approaches for lung cancer treatment, focusing on multifunctional nanocarriers.
- Strategies for optimizing nanotherapeutics include tailoring size, drug loading, transport, and retention for enhanced efficacy.
Key Points:
- Nanotechnology-based drug delivery systems show promise for more effective lung cancer treatment with fewer adverse effects.
- Personalized lung tumor therapies utilizing nano modalities can leverage genetic markers and disease profiles for tailored treatment.
- Research is advancing nanotherapeutic strategies to improve apoptosis management in lung cancer.
Conclusions:
- Nano-enabled approaches represent a significant advancement in improving lung cancer treatment outcomes.
- Tailored nanomedicines hold potential for personalized oncology, addressing individual patient needs and improving therapeutic effectiveness.

