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Updated: Sep 27, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Bakuchiol - a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
T P Adarsh Krishna1, Baldev Edachery1, Sunil Athalathil1
1R & D Division, Sreedhareeyam Farmherbs India Pvt. Ltd Ernakulam (Dist.) Kerala India-686 662 adarshkrishnatp@gmail.com.
Abstract:
Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea corylifolia. It has been reported to possess a broad range of biological and pharmacological properties and is considered as a leading biomolecule. It is highly desirable to devise an efficient approach to access bakuchiol and its chemical biology applications. In this review we provided structural features, isolation methods, various chemical routes and late-stage functionalization (LSF) approaches for bakuchiol and its derivatives. Moreover, this review encompasses the structure-activity relationships (SAR), value-added contributions and future perspectives of bakuchiol.
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