Pulsed Magnetic Field Treatment for Calming Neuroinflammation in Pain Conditions

Neuroinflammation can be associated with inflammatory mediators, such as cytokines and chemokines, that follow damage, injury, infection, or illness in the peripheral nervous system (PNS) and/or the central nervous system (CNS). These can play strategic roles in the formation and continuation of abnormal pain behaviors. Pulsed magnetic field (PMF) treatments have attracted attention for the prevention and management of various pain conditions.

The review intended to examine the mechanisms underlying the documented anti-neuroinflammatory effects of PMF treatment and its beneficial effects for neuroinflammatory pain states.

The research team performed a narrative review by searching for articles in the PubMed databases. The search used the keywords, pulsed magnetic field, neuroinflammation, cytokines, chemokines, pain, alone and in combination, without the restriction of the publication date.

This study was take place in faculty of medicine, Usak University, Usak, Turkey.

Neuroinflammation is a very complex process with the contribution of many inflammatory cells and their mediators. PMF treatment may modulate the neuroinflammatory conditions in the central and peripheral neural tissues.

The noninvasive PMF therapy, which has parameters that can be controlled and which has no side effects, is a nonpharmacological therapeutic option with pain-relief ability through strong control of central and peripheral neuroinflammation. Further studies are needed to explore how PMF therapy controls central and peripheral neuroinflammation in various diseases and conditions.