Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anionic Chain-Growth Polymerization: Overview

Anionic Chain-Growth Polymerization: Overview

The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spatially Resolved Diffusion NMR for Structurally Heterogeneous Materials.

Analytical chemistry·2026

Same author

Lithium-selective supramolecular assembly and capture by tripeptide gelators.

Chemical science·2026

Same author

Shear-Induced Anisotropic Supramolecular Gel Noodles for Improved Cell Guidance in Polarized Tissue Engineering.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

Tutorial: Machine-Learning-Based CREASE-2D Analysis of 2D SAXS Profiles to Characterize Anisotropic Nanostructures in Soft Materials.

ACS measurement science au·2026

Same author

Functionalized azobenzenes for micellar solar thermal energy storage as a next-generation MOST system.

Communications chemistry·2025

Same author

N-Terminal Hydrogen Bonding Initiates Morphology Transition from Flat to Twisted Ribbon in an Amphiphilic Dipeptide Gel.

Biomacromolecules·2025

Search research articles

Related Experiment Video

Updated: Sep 26, 2025

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

Chemical crosslinking in 'reactive' multicomponent gels.

Santanu Panja¹, Dave J Adams¹

¹School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK. dave.adams@glasgow.ac.uk.

Chemical Communications (Cambridge, England)

|April 19, 2022

Summary

The hydrolysis of EDC triggers covalent crosslinking in multicomponent gels. This process yields amide-functionalized gels with improved mechanical properties.

Area of Science:

Materials Science
Polymer Chemistry
Supramolecular Chemistry

Background:

Multicomponent gels offer tunable properties but often lack robust mechanical stability.
Developing effective crosslinking strategies is crucial for enhancing gel performance.

Purpose of the Study:

To investigate the use of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) hydrolysis for covalent crosslinking in multicomponent gels.
To create amide functionalized gels with enhanced mechanical properties.

Main Methods:

Utilizing EDC hydrolysis as a reactive system to induce crosslinking.
Employing gelators with carboxylic acid and amine functional groups.

Main Results:

Successfully triggered permanent covalent crosslinking between gel components.

More Related Videos

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Related Experiment Videos

Last Updated: Sep 26, 2025

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Formed amide functionalized gels with significantly enhanced mechanical properties.

Conclusions:

EDC hydrolysis is an effective method for creating covalently crosslinked multicomponent gels.
The resulting amide functionalized gels exhibit superior mechanical performance for potential applications.