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Updated: Sep 26, 2025
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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
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Thoracoabdominal Normothermic Regional Perfusion for Cardiac Procurement
David L Joyce1, Samuel F Carlson, Takushi Kohmoto
1From the Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.
ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|April 19, 2022
Summary
Thoracoabdominal normothermic regional perfusion (TANRP) aids cardiac transplantation by limiting warm ischemia time in donation after circulatory death donors. This technique improves organ recovery and monitoring, enhancing transplant success rates.
Area of Science:
- Cardiology
- Transplantation Surgery
- Organ Preservation
Background:
- Warm ischemia time poses a significant risk to successful cardiac transplantation in donation after circulatory death (DCD) donors.
- Rapid organ perfusion post-mortem is critical to minimize warm ischemic time and preserve cardiac viability.
Purpose of the Study:
- To present clinical practice pearls for streamlining the setup of a Thoracoabdominal Normothermic Regional Perfusion (TANRP) circuit.
- To ensure team familiarity with TANRP procedures during DCD cardiac procurements.
Main Methods:
- Utilized bicaval cannulation via the abdomen for aortic cannulation and via the chest for right atrial cannulation.
- Implemented a technique to minimize deairing maneuvers and reduce the time from incision to cardiopulmonary bypass initiation.
Main Results:
- The described techniques facilitate efficient setup of the TANRP circuit.
- The cannulation strategy aims to shorten the critical period of warm ischemia.
Conclusions:
- TANRP is a promising strategy for recovering and monitoring hearts from DCD donors.
- Standardized practice techniques can optimize TANRP implementation, improving outcomes in cardiac transplantation.
