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Transaminase Elevation in Nutritional Infantile Failure to Thrive
Kristen A Marten1, Nicole E St Clair2, Daniel M O'Connell2
1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, KMarten@uwhealth.org.
Introduction:
Laboratory investigations pursued for infants with failure to thrive (FTT) often show mild transaminase elevations, the incidence and significance of which are unknown.
Methods:
This retrospective chart review included infants diagnosed with simple nutritional FTT at a single academic tertiary care system. Comparisons of diagnostic studies and outcomes between children with and without transaminase elevation were performed using chi-square and Wilcoxon rank sum tests.
Results:
None of the infants with abnormal transaminases required additional follow-up or developed alternative diagnoses in the following year.
Discussion:
Transaminase elevation may be common in infants with FTT and may not warrant further investigation if the history indicates an isolated etiology of insufficient nutrition.
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