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Related Experiment Video

Updated: Sep 25, 2025

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
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Novel Devices for Sinus Headache.

Amar Miglani1, Zachary Soler2, Rodney J Schlosser3

  • 1Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA; Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Rutledge Tower,135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA.

Otolaryngologic Clinics of North America
|April 28, 2022
PubMed
Summary

Novel medical devices offer low-risk options for sinus headaches. Transcutaneous electrical neurostimulation and acoustic vibration may complement traditional treatments, but more research is needed.

Keywords:
Acoustic vibration with oscillating expiratory pressureMedical devicesSinus headachesTranscutaneous microcurrent electrical neurostimulationTreatment of sinus headaches

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Area of Science:

  • Neurology
  • Medical Device Technology

Background:

  • Sinus headaches are a common ailment.
  • Conventional pharmacotherapy is the primary treatment for sinus headaches.
  • Emerging medical devices show promise as adjunctive therapies.

Purpose of the Study:

  • To review novel medical devices for sinus headache management.
  • To assess the potential of these devices as adjuncts to pharmacotherapy.

Main Methods:

  • Literature review of emerging medical devices for sinus headaches.
  • Analysis of early data on transcutaneous electrical neurostimulation (TENS) and acoustic vibration with oscillating expiratory pressure (AVOEP).

Main Results:

  • Two categories of devices show early supporting data: TENS and AVOEP.
  • These devices may be useful adjuncts for sinus headaches not caused by sinusitis.
  • Initial reports indicate low risk, but longer follow-up is required.

Conclusions:

  • Novel medical devices represent a potential low-risk treatment avenue for sinus headaches.
  • Further high-level evidence is necessary to establish efficacy and long-term safety.
  • TENS and AVOEP warrant further investigation as complementary therapies.