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Updated: Sep 25, 2025
05:49
Protein Engineering by Yeast Surface Display
Published on: November 29, 2024
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Yeast Surface Display: New Opportunities for a Time-Tested Protein Engineering System.
Maryam Raeeszadeh-Sarmazdeh1, Eric T Boder2
1Department of Chemical and Materials Engineering, University of Nevada, Reno, NV, USA. maryamr@unr.edu.
Methods in Molecular Biology (Clifton, N.J.)
|April 28, 2022
Summary
Yeast surface display is a powerful method for discovering and engineering proteins like antibodies. This technique has expanded over decades to address challenging protein engineering and characterization problems.
Area of Science:
- Biotechnology
- Molecular Biology
- Protein Engineering
Background:
- Yeast surface display is a well-established technique.
- Its applications have significantly broadened since its inception.
Purpose of the Study:
- To summarize the evolution of yeast display methodologies.
- To highlight recent applications in protein engineering and characterization.
Main Methods:
- Review of yeast display development.
- Case studies of recent applications.
Main Results:
- Yeast display has evolved into a versatile tool.
- Numerous successful applications in protein engineering and characterization have been demonstrated.
Conclusions:
- Yeast surface display remains a critical technology.
- It continues to enable advancements in protein science and therapeutic development.
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