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IRBs and the Protection-Inclusion Dilemma: Finding a Balance
Phoebe Friesen1, Luke Gelinas2, Aaron Kirby3
1McGill University.
The American Journal of Bioethics : AJOB
|April 28, 2022
Summary
Institutional Review Boards (IRBs) face a dilemma: protecting participants while including diverse populations in research. This study examines this tension and offers recommendations for balancing protection and inclusion in ethical oversight.
Area of Science:
- Bioethics
- Research Ethics
- Health Policy
Background:
- Institutional Review Boards (IRBs) are crucial for ethical research oversight.
- IRBs navigate competing priorities between participant protection and research inclusion.
- Historical protectionism in US research ethics has influenced IRB practices.
Purpose of the Study:
- To define and examine the protection-inclusion dilemma faced by IRBs.
- To analyze historical context and responses to protectionism in research ethics.
- To offer recommendations for balancing protection and inclusion in IRB decision-making.
Main Methods:
- Literature review on research ethics and IRB decision-making.
- Analysis of historical trends in US research ethics oversight.
- Examination of inclusion initiatives and critiques of "vulnerability" in research.
Main Results:
- IRB decision-making often prioritizes protection over inclusion due to regulatory guidance.
- Lack of clear guidance exacerbates the protection-inclusion dilemma.
- Existing frameworks may inadvertently limit the inclusion of under-represented groups.
Conclusions:
- IRBs face significant challenges in balancing participant protection and research inclusion.
- Recommendations are proposed to foster a more equitable balance in ethical research oversight.
- Addressing the protection-inclusion dilemma is vital for advancing inclusive research practices.
Keywords:
IRB (Institutional Review Board)biomedical researchgender/sexualityhuman subjects researchrace and culture/ethnicityresearch ethicsMore Related Videos
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