Photo-triggered cargo release from liposome chlorin e6-bearing pullulan hybrid nanoparticles via membrane
Riku Kawasaki1, Reo Ohdake1, Takuro Eto1
1Program of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi Hiroshima 739-8527 Japan riku0528@hiroshima-u.ac.jp aikeda@hiroshima-u.ac.jp.
Abstract:
A liposome chlorin e6-bearing pullulan nanogel hybrid was prepared as a light-triggered payload release platform. The current system enabled manipulation of the release profile of model drugs encapsulated by liposomes. Gelatin hydrogels that comprised hybrid nanoparticles could successfully control the delivery of cargo molecules to human mesenchymal stem cells with light stimuli without injury to the cells.
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