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Updated: Sep 25, 2025

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
A Compact and Sensitive Time-Resolved-Optical-Reader for Bioassay Using Low-Energy Excitable and
Tristan Hegseth1, Bryan Lee1, David AuCoin2
1Department of Electrical and Biomedical Engineering, University of Nevada Reno, NV 98557 USA.
Abstract:
Time-resolved fluorescence measurement, a technique utilized to improve sensitivity for fluorescence detection, is becoming more accessible due to the recent development of bright nanolabels with long fluorescence lifetimes and low-energy excitation. Currently, instruments taking advantage of this technique for broader applications (in-field or point-of-care testing) are lagging behind in their development. In this work, a low-cost, compact, and sensitive time-resolved-optical-reader was developed aiming to advance such a technique for wider applications.

