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Related Experiment Video

Updated: Jan 16, 2026

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps
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A Miniature, Broadband Focused PVDF-TrFE PMUT with Interface ASIC for High-Resolution IVUS Imaging.

Ruiyan Wang1, Dave Dudzinski2, Russell J Fedewa2

  • 1Electrical, Computer, and Systems Engineering Department, Case Western Reserve University, Cleveland, OH 44106 USA.

IEEE Sensors Letters
|October 6, 2025
PubMed
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This summary is machine-generated.

This study introduces novel piezoelectric micromachined ultrasonic transducers (PMUTs) for high-resolution intravascular ultrasound (IVUS) imaging. The developed system achieves superior resolution and penetration depth, advancing miniaturized IVUS applications.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Medical Imaging

Background:

  • Intravascular ultrasound (IVUS) is crucial for high-resolution imaging of vascular structures.
  • Existing IVUS systems face limitations in miniaturization and resolution.
  • Piezoelectric micromachined ultrasonic transducers (PMUTs) offer potential for advanced IVUS probes.

Purpose of the Study:

  • To develop and characterize a novel, miniaturized IVUS system utilizing focused PMUTs.
  • To evaluate the imaging performance, including resolution and penetration depth, of the developed IVUS system.
  • To demonstrate the suitability of the system for visualizing vascular anatomy and stent structures.

Main Methods:

  • Fabrication of focused 0.8-mm aperture IVUS PMUTs using a PVDF-TrFE piezoelectric copolymer.
Keywords:
Intravascular ultrasound imaging (IVUS)Piezoelectric micromachined ultrasonic transducers (PMUTs)Polyvinylidene fluoride-co-trifluoro ethylene (PVDF-TrFE)Ultrasonic transducer

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  • Integration of PMUTs with a high-voltage-tolerant Analog Front End Application Specific Integrated Circuit (AFE-ASIC) on a custom PCB.
  • Characterization of transducer performance, including center frequency, bandwidth, axial, and lateral resolution.
  • Acquisition of IVUS images from stent phantoms and vascular tissue.

    • Main Results:

    • PMUTs achieved center frequencies >40 MHz with a -6 dB bandwidth up to 92%.
    • The system demonstrated an axial resolution of 20 μm and lateral resolution up to 75 μm at a 2.4 mm focal depth.
    • IVUS imaging successfully resolved vessel layers and stent struts with a 5 mm penetration depth.

    Conclusions:

    • The developed focused PMUT-based IVUS system provides high-resolution imaging capabilities.
    • The system's performance is suitable for miniaturized IVUS applications.
    • This technology advances the potential for detailed intravascular imaging and analysis.