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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

414
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
414
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

358
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
358
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

436
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
436
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

548
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
548
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

259
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
259
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

236
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
236

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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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A Tale of Two Colitides.

Noelle Provenzano1, Lindsey Forker2, Lorin Berman2

  • 1Internal medicine, Einstein Medical Center Montgomery, East Norriton, USA.

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Summary

Microscopic colitis (MC) and inflammatory bowel disease (IBD) rarely occur together. This case report details a rare instance of concurrent collagenous colitis and ulcerative colitis with distinct symptoms in one patient.

Keywords:
chronic colitiscrohn’s disease (cd)inflammatory bowel diseasemicroscopic colitisulcerative colitis (uc)

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Area of Science:

  • Gastroenterology
  • Colitis Research
  • Digestive Diseases

Background:

  • Inflammatory bowel disease (IBD) and microscopic colitis (MC) are distinct colitides.
  • MC presents as collagenous colitis (CC) or lymphocytic colitis (LC).
  • Co-occurrence of MC and IBD is exceptionally rare, with limited documented cases.

Observation:

  • A 76-year-old male presented with concurrent CC and ulcerative colitis (UC).
  • The patient experienced bloody diarrhea during the UC flare.
  • Watery diarrhea was indicative of the CC flare.

Findings:

  • This is the first reported case of concurrent CC and UC with distinct clinical presentations.
  • The distinct diarrheal patterns (bloody for UC, watery for CC) aided in diagnosis.
  • The study highlights the possibility of coexisting colitides with differing manifestations.

Implications:

  • This case expands the understanding of colitis presentations.
  • It suggests the need for thorough differential diagnosis in complex colitis cases.
  • Further research may explore the mechanisms and clinical significance of coexisting MC and IBD.