A nanodevice with lifetime-improved singlet oxygen for enhanced photodynamic therapy
A-Min Cao1, Wen-Long Liu1, Mei-Zhen Zou2
1Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science, School of Chemistry and Materials Science, South-Central Minzu University, Wuhan, 430074, P. R. China. wenlong@whu.edu.cn.
Chemical Communications (Cambridge, England)
|May 5, 2022
Abstract:
The short lifetime of singlet oxygen reduces its accumulation in the endoplasmic reticulum, which limits the output of photodynamic therapy. A nanodevice with functions of singlet oxygen production, storage and release can improve the lifetime of singlet oxygen for enhancing phototherapeutic efficacy.
