Related Experiment Video
Updated: Sep 24, 2025

07:38
Strategies for Assessing Autistic-Like Behaviors in Mice
Published on: September 20, 2024
1.3K
"Déjà vu" in an autism gene mouse model modifies social mores
Qiang-Qiang Xia1, Prathibha Sekar1, Craig M Powell1
1Department of Neurobiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA; Civitan International Research Center at UAB Heersink School of Medicine, Birmingham, AL, USA.
Neuron
|May 5, 2022
Abstract:
Genetic and environmental factors during development are involved in autism, and in this issue of Neuron Krüttner et al. (2022) find environment may play a more acute role in modulating autism behavior in a Shank3 exon 21 deletion mutant mouse (Shank3ΔC/ΔC). The authors explore the underlying circuit mechanisms in detail.

