Related Experiment Video
Updated: Sep 24, 2025

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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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Simulation versus live tissue training randomised trial for ECMO proficiency: is one better than the other?
Thornton Mu1, Tricia Garcia-Choudary2, Amanda Staudt2
1Pediatrics, Brooke Army Medical Center, JBSA Ft Sam Houston, Texas, USA.
BMJ Simulation & Technology Enhanced Learning
|May 6, 2022
Summary
Extracorporeal membrane oxygenation (ECMO) training using simulation models resulted in faster task completion times compared to animal models. Both training modalities effectively maintained ECMO skill competency.
Area of Science:
- Medical Education
- Cardiopulmonary Bypass
- Simulation Technology
Background:
- Extracorporeal membrane oxygenation (ECMO) is a critical, high-risk procedure requiring specialized, up-to-date training.
- Traditional training methods include animal models and simulation, with ongoing debate regarding their comparative efficacy.
Purpose of the Study:
- To evaluate and compare the performance of ECMO personnel trained using simulation versus live animal models.
- To determine the optimal modality for ECMO skills acquisition and maintenance.
Main Methods:
- Physicians, nurses, and technicians underwent ECMO training scenarios using both synthetic tissue simulators and live animal models.
- Objective performance was assessed using a validated ECMO skills assessment tool, focusing on task completion and time.
Main Results:
- Simulation training led to significantly faster individual task completion times (26 min vs. 29 min; p=0.03).
- Participants using simulators completed a higher percentage of critical tasks in group scenarios (97% vs. 91%; p=0.05).
- No significant differences were observed in individual task completion rates or cognitive scores between the two training modalities.
Conclusions:
- Both simulation and animal models are beneficial for developing and maintaining ECMO skill competency.
- Simulation training offers potential advantages in efficiency and critical task performance.
- Simulation may serve as a viable alternative or supplement to live tissue training, addressing cost and ethical considerations.

