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Clinically Localized Prostate Cancer: AUA/ASTRO Guideline. Part III: Principles of Radiation and Future Directions
James A Eastham1, Gregory B Auffenberg2, Daniel A Barocas3
1Memorial Sloan Kettering Cancer Center, New York, New York.
The Journal of Urology
|May 10, 2022
Summary
This guideline provides evidence-based recommendations for radiation therapy in managing clinically localized prostate cancer. Future research is crucial for advancing treatment strategies and improving patient outcomes.
Area of Science:
- Urology
- Radiation Oncology
Background:
- This is Part III of a series on the AUA/ASTRO Guideline for Clinically Localized Prostate Cancer.
- Previous parts covered risk assessment, staging, management, active surveillance, and surgery.
Purpose of the Study:
- To present evidence- and consensus-based guideline statements for managing clinically localized prostate cancer using radiation therapy.
- To outline future research directions in the field.
Main Methods:
- A systematic review informed the guideline development.
- Searches were conducted in Ovid MEDLINE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews.
- The methodology team supplemented database searches with existing relevant studies.
Main Results:
- Guideline statements focus on radiation therapy principles for localized prostate cancer.
- Key future research areas are identified to enhance patient care.
Conclusions:
- The guideline assists clinicians in treating patients with localized prostate cancer.
- High-quality evidence from future trials is essential for improving patient care.
