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Updated: Sep 23, 2025

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
Published on: September 6, 2019
Efficient conversion of glucosamine to levulinic acid in a sulfamic acid-catalyzed hydrothermal reaction
Hyo Seon Kim1, Sung-Koo Kim1, Gwi-Taek Jeong1
1Department of Biotechnology, Pukyong National University Busan 48513 Republic of Korea gtjeong@pknu.ac.kr +82-51-629-5863 +82-51-629-5869.
Abstract:
Glucosamine is a monomer of chitosan, which is a biopolymer derived from the exoskeletons of crustaceans. This work investigated the conversion of glucosamine into the platform chemical levulinic acid (LA), in a sulfamic acid-catalyzed hydrothermal reaction. The optimized results of LA production showed that the conditions of 200 °C, 125 g L-1 glucosamine, 0.3 M sulfamic acid, and 15 min produced a 33.76 ± 0.19 mol% LA yield. The same conditions produced only 0.14 mol% 5-HMF yield. These results show that glucosamine is a potential bioresource to produce platform chemicals. Also, in the field of biofuels and chemical synthesis processes, the catalytic system using sulfamic acid is significant.
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