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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Related Experiment Video

Updated: Sep 23, 2025

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
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Lung Cancer: Diagnosis, Treatment Principles, and Screening.

Jeffrey Kim1, Hobart Lee1, Brian W Huang1

  • 1Loma Linda University School of Medicine, Loma Linda, CA, USA.

American Family Physician
|May 13, 2022
PubMed
Summary

Lung cancer is a leading cause of cancer death. Early recognition through screening and prompt diagnosis are crucial for effective treatment and improved outcomes.

Area of Science:

  • Oncology
  • Pulmonology
  • Public Health

Background:

  • Lung cancer is the second most common cancer and the leading cause of cancer-related death globally.
  • Nonspecific symptoms like cough, hemoptysis, shortness of breath, anorexia, and weight loss can indicate lung cancer.
  • Early detection and intervention are critical for improving patient survival rates.

Purpose of the Study:

  • To summarize current understanding of lung cancer diagnosis and treatment.
  • To emphasize the role of primary prevention and early screening in managing lung cancer.
  • To highlight updated screening guidelines for high-risk individuals.

Main Methods:

  • Review of clinical presentation and diagnostic procedures for lung cancer.
  • Discussion of treatment modalities based on cancer staging, histology, and patient status.

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  • Emphasis on primary prevention strategies, including tobacco cessation and screening.

    • Main Results:

    • Symptoms like cough, hemoptysis, and weight loss increase the likelihood of lung cancer.
    • Diagnostic confirmation involves imaging, sputum cytology, thoracentesis, fine-needle aspiration, or mediastinoscopy.
    • Treatment options encompass surgery, immunotherapy, chemotherapy, and radiotherapy.

    Conclusions:

    • Family physicians play a key role in primary prevention via tobacco cessation and early screening.
    • Annual low-dose computed tomography screening is recommended for individuals aged 50+ with a 20 pack-year smoking history.
    • Multidisciplinary team referral and tailored treatment based on individual patient factors are essential for optimal lung cancer management.