Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Finite-element modelling of the 3D motion of the malleus-incus complex validated with 3D laser Doppler vibrometry.

Hearing research·2025
Same author

Minimally Invasive Intraoperative Laser Vibrometry (MIVIB)-A Peroperative Method to Measure Fixation of the Ossicular Chain.

Laryngoscope investigative otolaryngology·2025
Same author

Deep Learning for Single-Shot Structured Light Profilometry: A Comprehensive Dataset and Performance Analysis.

Journal of imaging·2024
Same author

Prestrain in the eardrum investigated using laser-ablation perforation: A proof of principle study on the New Zealand white rabbit.

Hearing research·2023
Same author

Blowing pressure stabilization method for the artificial excitation of reed instruments (L).

The Journal of the Acoustical Society of America·2023
Same author

Rabbit tympanic membrane thickness distribution obtained via optical coherence tomography.

Hearing research·2023

Related Experiment Video

Updated: Sep 23, 2025

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
07:16

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques

Published on: October 20, 2023

1.4K

How does prestrain in the tympanic membrane affect middle-ear function? A finite-element model study in rabbit.

Pieter G G Muyshondt1, Joris J J Dirckx1

  • 1University of Antwerp, Biophysics and Biomedical Physics, Groenenborgerlaan 171, B-2020, Antwerp, Belgium.

Journal of the Mechanical Behavior of Biomedical Materials
|May 13, 2022
PubMed
Summary
This summary is machine-generated.

Prestrain in the rabbit tympanic membrane significantly impacts middle ear vibrations, affecting sound response. Understanding this prestrain is crucial for modeling ear function and disease.

Keywords:
Finite-element analysisMiddle earPrestrainRabbitTympanic membrane

More Related Videos

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
08:42

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit

Published on: November 21, 2023

1.3K
Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat
06:27

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Published on: October 26, 2019

7.8K

Related Experiment Videos

Last Updated: Sep 23, 2025

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
07:16

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques

Published on: October 20, 2023

1.4K
A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
08:42

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit

Published on: November 21, 2023

1.3K
Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat
06:27

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Published on: October 26, 2019

7.8K

Area of Science:

  • Biomechanics
  • Computational Biology
  • Otolaryngology

Background:

  • Prestrain exists in the rabbit tympanic membrane (TM) even without external loads.
  • The influence of TM prestrain on middle ear (ME) vibration response remains unclear.

Purpose of the Study:

  • To investigate the effect of TM prestrain on ME vibration response using a 3D finite-element model.
  • To analyze how TM prestrain changes in pathological conditions, such as TM perforation.

Main Methods:

  • Developed a 3D finite-element model of the rabbit ME with experimentally validated material properties.
  • Incorporated varying degrees of TM prestrain and simulated ME vibration response to sound.
  • Utilized a framework to handle finite deformations associated with large prestrains.

Main Results:

  • Small levels of TM prestrain substantially impact umbo and footplate response due to prestress stiffening.
  • TM perforation alters vibration response at low frequencies due to a release of TM prestrain.
  • Prestrain effects in the normal ME could be replicated by scaling elastic moduli and damping factors.

Conclusions:

  • Prestrain significantly influences ME vibration response, particularly in normal and perforated TM conditions.
  • Incorporating prestrain into ME models is necessary for a better understanding of diseased or reconstructed ears.
  • This research is relevant for developing reconstructive tissue grafts for the middle ear.