Analysis of Intracellular and Extracellular Selenium Concentrations: Differences According to Training Level

Area of Science:

• Human Physiology
• Nutritional Biochemistry
• Sports Science

Background:

• Selenium (Se) is a crucial micronutrient vital for antioxidant and immune functions.
• Physical training may influence selenium metabolism and distribution within the body.
• Homeostatic control regulates trace mineral element concentrations.

Purpose of the Study:

• To investigate extracellular and intracellular selenium concentrations in athletes versus sedentary individuals.
• To compare selenium levels in plasma, urine, serum, platelets, and erythrocytes between trained and untrained groups.

Main Methods:

• Study included forty young men, divided into a control group (CG) and a training group (TG) of semi-professional soccer players.
• Selenium concentrations were quantified using inductively coupled plasma mass spectrometry (ICP-MS).
• Maximal oxygen consumption and muscle percentage were assessed to confirm training status.

Main Results:

• The training group exhibited significantly higher maximal oxygen consumption and muscle percentage.
• Athletes (TG) demonstrated significantly lower absolute and relative selenium concentrations in erythrocytes and platelets compared to the control group (CG).
• Extracellular selenium levels (plasma, serum, urine) were not detailed in comparison between groups in the provided abstract.

Conclusions:

• Intensive physical training is associated with reduced intracellular selenium levels in blood cells.
• Trace element assessments require consideration of intracellular compartments, not solely extracellular measurements.
• Potential intracellular selenium deficiencies may exist in athletes despite normal extracellular levels.