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On the interface between biomaterials and two-dimensional materials for biomedical applications.

Chunbao Du1, Ting Du1, Zixi Chang1

  • 1College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, PR China.

Advanced Drug Delivery Reviews
|May 14, 2022
PubMed
Summary

This review explores two-dimensional (2D) materials and their interfaces with biomaterials for advanced biomedical applications. It highlights material properties, interactions, and manufacturing techniques for novel 2D biomaterial composites.

Keywords:
2D biomaterials2D materialsAssemblyBiomaterialsBiomedicalCharacterizationExfoliation

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Nanoscience

Background:

  • Two-dimensional (2D) materials possess unique ultrathin structures, high anisotropy, and inherent functionality.
  • The interface between 2D materials and biomaterials is a critical area for developing advanced biomedical nanoscience.
  • Combining biomaterials with 2D materials enables the creation of innovative composites with tailored functionalities.

Purpose of the Study:

  • To summarize current research on the interface investigation of 2D biomaterials.
  • To highlight the desirable features of 2D materials and their molecular-level interactions with biomaterials.
  • To review methods for investigating interface characteristics and advancements in biomaterial-assisted exfoliation for mass production.

Main Methods:

  • Literature review focusing on interface investigations of 2D biomaterials.
  • Analysis of molecular interactions between 2D materials and biomaterials.
  • Examination of techniques for interface characterization and biomaterial-assisted exfoliation.

Main Results:

  • Identification of extraordinary features of 2D materials relevant to biomedical applications.
  • Summary of studied molecular-level interactions between 2D materials and biomaterials.
  • Overview of approaches for interface investigation and progress in mass manufacturing via biomaterial-assisted exfoliation.

Conclusions:

  • The interface between 2D materials and biomaterials is a promising frontier for innovative biomedical applications.
  • Understanding molecular interactions and interface characteristics is key to developing novel 2D biomaterial composites.
  • Biomaterial-assisted exfoliation shows potential for the mass production of these advanced materials.