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Immunohematological provision of red blood cells transfusions to alloimmunized recipients (clinical case)

A V Yovdiy1, E V Butina1, E A Poponina1

  • 1Federal State Budget Institution of Science "Kirov Scientific Research Institute of Hematology and Blood Transfusion of the Federal Medical-Biological Agency".

Klinicheskaia Laboratornaia Diagnostika
|May 16, 2022
PubMed

Timely diagnostics of red blood cells (RBC) antibodies and selection of immunologically compatible donors can prevent the occurrence of hemolytic transfusion reactions in recipients of RBC. The article presents an analysis of a clinical case describing the variability of the antibody screening results and the difficulties of individual selection of donors for a alloimmunized patient with myelodysplastic syndrome. The basic immunohematological principles have been formulated to ensure the safety of transfusions in patients with RBC antibodies.

Keywords:
alloantibodiesantigensindividual selection of donorsred blood cellstransfusion therapy

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