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What Is the Medication Iatrogenic Risk in Elderly Outpatients for Chronic Pain?
Julie Jambon1, Chloé Choukroun, Clarisse Roux-Marson
1Department of Pharmacy, Nimes University Hospital, University of Montpellier, Nimes.
Clinical Neuropharmacology
|May 17, 2022
Summary
Elderly chronic pain patients face significant medication iatrogenic risk. Multidisciplinary medication reviews are recommended to reduce harm from inappropriate prescriptions and polypharmacy.
Area of Science:
- Geriatric Medicine
- Clinical Pharmacy
- Pharmacovigilance
Background:
- Medication iatrogeny is a growing public health concern, particularly in aging populations.
- Therapeutic escalation for pain management can exacerbate polypharmacy and iatrogenic risk.
- Characterizing this risk in elderly chronic pain outpatients is crucial for patient safety.
Purpose of the Study:
- To assess the medication iatrogenic risk in elderly outpatients suffering from chronic pain.
- To identify specific prescribing patterns contributing to iatrogenic risk in this demographic.
Main Methods:
- Prospective cohort study of 100 patients aged 65+ with chronic pain.
- Medication iatrogenic risk assessment using Trivalle score, STOPP/START criteria, and identification of potentially inappropriate medications.
- Analysis of medication history and prescription patterns.
Main Results:
- 43% of patients exhibited moderate to high iatrogenic risk (Trivalle score).
- High prevalence of potentially inappropriate medications: 79% met STOPP criteria, 75% met START criteria.
- 54% received at least one potentially inappropriate medication; 23% were prescribed multiple anticholinergics.
Conclusions:
- Elderly chronic pain outpatients are at substantial risk of medication iatrogeny.
- Preventive strategies, including multidisciplinary medication reviews, are essential to mitigate this risk.
- Findings highlight the need for targeted interventions to improve medication safety in this vulnerable population.
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