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Updated: Sep 22, 2025

Thermal Scanning Conductometry TSC as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels
Published on: January 23, 2018
Temperature, pH, and Glucose Responsive Gels via Simple Mixing of Boroxole- and Glyco-Based Polymers
Yohei Kotsuchibashi1, Roman Vincent C Agustin1, Jin-Yong Lu2
1Department of Chemical and Materials Engineering and Alberta Glycomics Centre, University of Alberta, Edmonton, Alberta, T6G 2G6, Canada.
Abstract:
Statistical copolymers of N-isopropylacrylamide (NIPAAm) and 5-methacrylamido-1,2-benzoxaborole (MAAmBo) have been synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. The solution properties of the NIPAAm homopolymers and statistical copolymers were investigated and it was found that, besides temperature and pH, the statistical copolymers were also responsive to the presence of free glucose in solution. Furthermore, responsive hydrogels and nanogels were formed spontaneously by simply mixing the statistical copolymers of P(NIPAAm-st-MAAmBO)s and well-defined glycopolymers. These gels were found to have temperature, pH, and glucose responsive properties.
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