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Updated: Sep 22, 2025

Expression, Solubilization, and Purification of Eukaryotic Borate Transporters
Published on: March 7, 2019
Superchaotropic Boron Clusters as Membrane Carriers for the Transport of Hydrophilic Cargos
1College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
Abstract:
Design of membrane transporters is important in pharmaceutical drug delivery and bioimaging. Traditionally, the amphiphilic transport mechanism has governed the design of membrane carriers over the last 50 years. Recently, Montenegro, Nau and co-workers discarded classical amphiphilic models and proposed a new transport principle based on the chaotropic effect. They utilized globular boron clusters as membrane carriers to transport a broad range of hydrophilic cargo. Herein, we highlight this recent pioneering work, which is a landmark for membrane transport.
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