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Updated: Sep 22, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Minimed Medtronic 780G optimizes glucose control in patients with type 1 diabetes mellitus
Basilio Pintaudi1, Ilaria Gironi1, Riccardo Nicosia1
1SC Diabetologia, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Background And Aims:
The new advanced hybrid closed loop insulin infusion systems have the potential to significantly improve glycaemic control. The aim of this study was to evaluate the effectiveness of the Minimed 780G system in 59 patients with type 1 diabetes.
Methods And Results:
Glucose control obtained by using the system in automatic mode at 1-2 months of activation, at 2-4 months, at 4-6 months, and beyond 6 month was compared with those obtained with the system in manual mode. A significant improvement in time-in-range and in time-above-range throughout the follow-up was observed, as well as a significant reduction in time-below-range (<54 mg/dl) after 6 months, a significant reduction of the glucose variability and of HbA1c. After switching the mode, all target percentages lied on the average within the recommended ranges by literature consensus and no severe hypoglycemia nor ketoacidosis episodes were recorded.
Conclusion:
The Minimed 780G allowed a rapid and progressive improvement of the overall glucose control.
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