Related Experiment Video
Updated: Sep 22, 2025

A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
ED BP Management for Subarachnoid Hemorrhage.
W Denney Zimmerman1, Wan-Tsu W Chang2
1Department of Neurology, University of Maryland Medical Center, Baltimore, MD, 21201, USA.
Managing blood pressure in acute aneurysmal subarachnoid hemorrhage (SAH) is critical. Lowering systolic blood pressure (SBP) to 140-160 mmHg reduces rebleeding risk and improves outcomes.
Area of Science:
- Neurology
- Neurosurgery
- Emergency Medicine
Background:
- Aneurysmal subarachnoid hemorrhage (SAH) presents significant risks, including rebleeding.
- Elevated blood pressure (BP) and BP variability are associated with poorer outcomes in acute SAH.
- Understanding cerebral perfusion pressure (CPP) and autoregulation is vital for managing SAH patients.
Purpose of the Study:
- To review current literature on blood pressure management in acute aneurysmal subarachnoid hemorrhage (SAH).
- To provide evidence-based practice recommendations for emergency clinicians managing SAH.
- To optimize patient outcomes by addressing critical BP parameters.
Main Methods:
- Literature review of recent studies on aneurysmal SAH management.
- Analysis of the impact of systolic blood pressure (SBP) on rebleeding risk.
- Evaluation of strategies for BP control and CPP maintenance.
Main Results:
- Systolic blood pressure (SBP) > 160 mmHg increases the risk of aneurysmal rebleeding.
- Maintaining SBP in the 140-160 mmHg range reduces rebleeding and preserves CPP.
- Utilizing short-acting antihypertensive agents facilitates BP titration and reduces variability.
- Increased intracranial pressure is common, affecting cerebral autoregulation and CPP.
Conclusions:
- Acute lowering of SBP to 140-160 mmHg is recommended for aneurysmal SAH.
- Minimizing BP variability is crucial for improving clinical outcomes.
- Careful BP management is essential to prevent secondary neurological injury in SAH patients.
More Related Videos
Related Concept Videos
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Pre-Procedural Guidelines for Assessing Blood Pressure
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Aneurysm IV: Nursing Management
Assessment of blood pressure in brachial artery(two-step method)
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...

