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The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation

Giuseppe Cannino1, Andrea Urbani1, Marco Gaspari2

  • 1Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy.

Cell Death and Differentiation
|May 25, 2022
PubMed
Summary

Mitochondrial chaperone TRAP1 binds F-ATP synthase, boosting its activity and inhibiting cell death pathways. TRAP1 regulates cell energy and survival, offering a target for diseases like cancer.

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