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Updated: Sep 21, 2025
Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites
Published on: October 13, 2023
Computationally Assisted Structural Elucidation of Cembranoids from the Soft Coral Sarcophyton tortuosum
Chih-Hua Chao1,2, Kuan-Hua Lin3, Chiung-Yao Huang3
1School of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Abstract:
A persistent study on soft coral Sarcophyton tortuosum resulted in the characterization of two new cembranolides, tortuolides A and B (1 and 2), and a new related diterpene, epi-sarcophytonolide Q. Their structures were determined not only by extensive spectroscopic analysis but also by DFT calculations of ECD and NMR data, the latter of which was combined with statistical analysis methods, e.g., DP4+ and J-DP4 approaches. Anti-inflammatory and cytotoxicity activities were evaluated in this study.
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