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Comparing Digital Therapeutic Intervention with an Intensive Obesity Management Program: Randomized Controlled Trial.

Katarína Moravcová1, Martina Karbanová2,3, Maxi Pia Bretschneider4

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The digital Vitadio program shows comparable obesity management results to intensive in-person interventions. This effective tool supports patients in weight loss and diabetes prevention.

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diabetes mellitus type 2digital therapeuticsinsulin resistancelifestyle interventionmetabolic syndromemobile applicationobesitypreventionrandomized controlled trial

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Area of Science:

  • Metabolic disease management
  • Digital health interventions
  • Obesity research

Background:

  • Obesity is a complex metabolic condition requiring effective management strategies.
  • Digital health platforms offer scalable solutions for lifestyle interventions.
  • Comparing digital versus in-person programs is crucial for optimizing obesity care.

Purpose of the Study:

  • To evaluate the efficacy of the digital program Vitadio against intensive in-person lifestyle intervention for obesity management.
  • To compare the impact of digital versus traditional interventions on body weight and metabolic parameters in obese patients.
  • To assess Vitadio's effectiveness in patients with insulin resistance, prediabetes, or type 2 diabetes.

Main Methods:

  • A 12-month prospective, randomized controlled trial comparing Vitadio (intervention group) with in-person consultations (control group).
  • Inclusion criteria: Obese patients with insulin resistance, prediabetes, or type 2 diabetes.
  • Outcome measures: Body weight, body composition, and metabolic parameters (TAG, HDL, HbA1c, FG, HOMA-IR) analyzed using ANOVA.

Main Results:

  • Preliminary findings show significant body weight reduction at 3 and 6 months in both groups, with no significant difference between them.
  • The digital intervention group (Vitadio) demonstrated favorable changes in body composition.
  • Significant improvements were observed in TAG, HDL, HbA1c, FG, and HOMA-IR in the intervention group compared to baseline.

Conclusions:

  • The digital program Vitadio achieves comparable results to intensive in-person lifestyle interventions for obesity management.
  • Vitadio is a potentially effective tool for supporting patients in weight management and diabetes prevention.
  • Digital health interventions represent a viable and effective approach to managing obesity and related metabolic conditions.