Related Experiment Video
Updated: Sep 21, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Managing high blood pressure in hypertensive patients with an acute ischemic stroke
I Mursalov1, A Muneer2, R Aringazina3
1Department of Pediatry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.
Insights
In patients with arterial hypertension and acute ischemic stroke, higher diastolic blood pressure correlates with greater stroke severity and poorer outcomes. This highlights diastolic pressure as a key indicator for monitoring neurological deficits.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Arterial hypertension (AH) is a primary risk factor for acute cerebrovascular accidents.
- Understanding blood pressure management in acute ischemic stroke (AIS) is critical.
Purpose of the Study:
- To analyze blood pressure reduction patterns in AH patients during acute ischemic stroke.
- To examine how sex, age, medical history, and clinical factors influence these patterns.
Main Methods:
- Study included 120 patients (41-77 years) with diagnosed AH and AIS.
- Patients were monitored for 14 days post-stroke onset within 24 hours.
Main Results:
- Elevated diastolic blood pressure correlated with higher NIH Stroke Scale and Rankin scale scores.
- Increased diastolic pressure was linked to worse patient health status at hospital discharge.
Conclusions:
- Diastolic blood pressure serves as a marker for neurological disorder severity in AIS.
- Monitoring diastolic pressure is crucial for managing AIS patients with hypertension.
Introduction:
Arterial hypertension (AH) is one of the key risk factors and triggers for the development of acute cerebrovascular accident. The purpose of the study is to investigate the peculiarities and rates of blood pressure reduction in AH patients during the acute period of ischemic stroke depending on the patients' sex, age, medical history, and clinical characteristics.
Material And Methods:
The study involved 120 patients aged 41-77 years, of whom there were 47 (39.2%) men and 73 (60.8%) women. All enrolled patients had established diagnoses of AH and acute ischemic cerebrovascular accident (acute ischemic stroke, AIS), with the latter diagnosed within the first 24h from onset. The follow-up period was 14 days.
Results:
An increase in diastolic blood pressure was associated with higher scores on the National Institutes of Health Stroke Scale (NIHSS, r=0.301, p=0.026) and Rankin scale (r=0.225, p=0.030), as well as a worse health status at the time of discharge from hospital (r=0.318, p=0.021).
Conclusion:
Diastolic blood pressure can be considered a marker of the severity of neurological disorders in AIS, which should be considered when monitoring such patients.
More Related Videos
Related Concept Videos
Atherosclerosis IV: Nursing Management
Hypertension V: Nursing Management
Hypertension IV: Drug Therapy and Lifestyle Modifications
Atherosclerosis III: Management
Acute Coronary Syndrome IV: Interprofessional Care
Hypertension and Regulation of Blood Pressure

