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Dual pathogen valvular endocarditis in a case of severe aortic aneurysm
Meghna Yadav1, Rohit Tewari2, Tathagata Chatterjee2
1Base Hospital, Department of Pathology, New Delhi, India.
Autopsy & Case Reports
|June 1, 2022
Summary
This case report details a rare polymicrobial endocarditis caused by Aspergillus spp. and Acinetobacter baumannii, highlighting its poor prognosis and the need for clinical suspicion in complex cases.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Infective endocarditis (IE) involves infection of the heart valves or endocardium.
- Polymicrobial endocarditis (PE) is an uncommon but serious condition.
Observation:
- A 36-year-old male with aortic aneurysms presented with a fulminant clinical course.
- The patient had a history of degenerative aortic disease and multiple comorbidities.
- Autopsy confirmed dual pathogen endocarditis.
Findings:
- The autopsy revealed invasive Aspergillus spp. mycosis and Acinetobacter baumannii sepsis.
- This represents a rare instance of polymicrobial endocarditis involving these two pathogens.
- The patient experienced a fatal outcome despite challenging treatment efforts.
Implications:
- This case underscores the infrequent occurrence and poor prognosis associated with polymicrobial endocarditis.
- High clinical suspicion is crucial for diagnosing PE, especially in patients with comorbidities.
- Understanding rare polymicrobial IE contributes to improved diagnostic and therapeutic strategies.
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