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Dual pathogen valvular endocarditis in a case of severe aortic aneurysm

Meghna Yadav1, Rohit Tewari2, Tathagata Chatterjee2

  • 1Base Hospital, Department of Pathology, New Delhi, India.

Autopsy & Case Reports
|June 1, 2022
PubMed

Insights

This case report details a rare polymicrobial endocarditis caused by Aspergillus spp. and Acinetobacter baumannii, highlighting its poor prognosis and the need for clinical suspicion in complex cases.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathology

Background:

  • Infective endocarditis (IE) involves infection of the heart valves or endocardium.
  • Polymicrobial endocarditis (PE) is an uncommon but serious condition.

Observation:

  • A 36-year-old male with aortic aneurysms presented with a fulminant clinical course.
  • The patient had a history of degenerative aortic disease and multiple comorbidities.
  • Autopsy confirmed dual pathogen endocarditis.

Findings:

  • The autopsy revealed invasive Aspergillus spp. mycosis and Acinetobacter baumannii sepsis.
  • This represents a rare instance of polymicrobial endocarditis involving these two pathogens.
  • The patient experienced a fatal outcome despite challenging treatment efforts.

Implications:

  • This case underscores the infrequent occurrence and poor prognosis associated with polymicrobial endocarditis.
  • High clinical suspicion is crucial for diagnosing PE, especially in patients with comorbidities.
  • Understanding rare polymicrobial IE contributes to improved diagnostic and therapeutic strategies.
Keywords:
Acinetobacter baumanniiAneurysmAspergillusEndocarditis

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