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Updated: Sep 21, 2025

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Role of artificial intelligence in MS clinical practice
Raffaello Bonacchi1, Massimo Filippi2, Maria A Rocca1
1Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.
Artificial intelligence (AI), including machine learning (ML) and deep learning (DL), shows potential in analyzing medical imaging for multiple sclerosis (MS). While AI offers benefits like automation and accuracy, challenges in validation and integration require human oversight.
Area of Science:
- Artificial Intelligence
- Machine Learning
- Deep Learning
- Medical Imaging Analysis
Background:
- Multiple Sclerosis (MS) diagnosis and management heavily rely on Magnetic Resonance Imaging (MRI).
- Artificial intelligence (AI) techniques, particularly machine learning (ML) and deep learning (DL), demonstrate significant potential in medical imaging.
- MS presents an ideal use case for AI due to the critical role of MRI data.
Purpose of the Study:
- To review the potential applications of AI in the clinical practice of multiple sclerosis (MS).
- To discuss the limitations and challenges associated with implementing AI in MS care.
- To highlight the advantages of AI in processing and analyzing medical imaging data.
Main Methods:
- Narrative review of existing literature on AI applications in MS.
- Discussion of ML/DL algorithms applied to MS diagnosis, prognosis, and monitoring.
- Exploration of AI's role in improving MRI protocols and automated segmentation tasks.
Main Results:
- AI algorithms can automate repetitive tasks, analyze data faster, and improve accuracy and reproducibility in MS imaging.
- Current AI applications in MS include diagnosis, prognosis, disease/treatment monitoring, MRI protocol optimization, and lesion segmentation.
- AI demonstrates potential for enhancing efficiency and precision in the analysis of MS-related imaging data.
Conclusions:
- AI offers substantial benefits for multiple sclerosis clinical practice, particularly in analyzing MRI data.
- Key challenges include understanding AI decision-making, multicenter validation, and practical integration.
- Human supervision is crucial for optimizing AI's utility and realizing its full potential in MS management.

