Related Experiment Video
Updated: Sep 20, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Antiphospholipid autoantibodies and Covid-19]
Samuel Weber1, Nathalie Bardin1,2
1Service d'immunologie, pôle de biologie, hôpital de la Conception, AP-HM, 147 boulevard Baille, 13005 Marseille, France.
Abstract:
Infection with Sars-CoV-2 is at the origin of a viral pandemic responsible for an unprecedented global health and economic crisis. Recently, an autoimmune process has been described in particular in severe forms of Covid-19. However, the role of autoimmunity in the disease remains to be defined. Thus, the presence of antiphospholipid autoantibodies (aPLs) is observed in patients with Covid-19 and a significant association is demonstrated between patients with a severe form and the presence of anticardiolipin autoantibodies (aCL) of IgG isotype.
Related Concept Videos
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Myocarditis II: Clinical Features and Diagnostic Tests
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Conjugated Proteins
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Cross-reactivity

