Multimodal Imaging in Ocular Siderosis

Area of Science:

• Ophthalmology
• Medical Imaging
• Toxicology

Background:

• Ocular siderosis results from intraocular foreign bodies containing iron.
• Iron toxicity can lead to significant ocular changes and vision impairment.

Purpose of the Study:

• To characterize ocular alterations in a case of ocular siderosis with iron toxicity.
• To evaluate the utility of multimodal imaging and electroretinography in assessing ocular siderosis.

Main Methods:

• A case study of a 34-year-old female with ocular siderosis in the left eye after penetrating injury.
• Utilized cone contrast threshold (CCT), full-field electroretinogram, spectral-domain optical coherence tomography (OCT), and OCT angiography (OCTA).
• Evaluated ocular changes preoperatively and postoperatively after foreign body removal and cataract surgery.

Main Results:

• Preoperative CCT revealed abnormal color vision.
• OCT angiography (OCTA) demonstrated increased vascular flow density related to the iron foreign body.
• Successful surgical intervention led to no postoperative complications.

Conclusions:

• Cone contrast threshold (CCT) color vision testing is valuable for detecting visual deficits.
• OCT angiography (OCTA) can identify vascular changes associated with ocular siderosis.
• Multimodal imaging (OCT, OCTA) and electroretinography (full-field electroretinogram) are effective tools for characterizing retinal changes in ocular siderosis.